{"id":590,"date":"2021-01-01T13:00:03","date_gmt":"2021-01-01T13:00:03","guid":{"rendered":"https:\/\/ladomerylab.org\/?post_type=research_papers&#038;p=590"},"modified":"2023-03-04T11:17:57","modified_gmt":"2023-03-04T11:17:57","slug":"a-proteomic-analysis-of-oligodt-bound-mrnp-containing-oxidative-stress-induced-arabidopsis-thaliana-rna-binding-proteins-atgrp7-and-atgrp8","status":"publish","type":"research_papers","link":"https:\/\/ladomerylab.org\/research-papers\/a-proteomic-analysis-of-oligodt-bound-mrnp-containing-oxidative-stress-induced-arabidopsis-thaliana-rna-binding-proteins-atgrp7-and-atgrp8\/","title":{"rendered":"A proteomic analysis of oligo(dT)-bound mRNP containing oxidative stress-induced Arabidopsis thaliana RNA-binding proteins ATGRP7 and ATGRP8"},"content":{"rendered":"<p>Plants are highly adapted to respond to a range of environmental stresses commonly by altering their gene expression and metabolism as a result of cell signalling which may be mediated by reactive oxygen species. The glycine-rich\u00a0<span class=\"caps\">RNA<\/span>-binding proteins ATGRP7 and ATGRP8 were rapidly upregulated in response to peroxide-induced oxidative stress and were amongst the most abundant\u00a0<span class=\"caps\">RNA<\/span>\u00a0binding proteins isolated by oligo(dT) chromatography. The oligo(dT)-bound mRNP complexes were analysed proteomically, and were seen to contain potential isoforms of the\u00a0<span class=\"caps\">ATGRP<\/span>\u00a0proteins; other proteins that contain an\u00a0<span class=\"caps\">RNA<\/span>\u00a0Recognition Motif (<span class=\"caps\">RRM<\/span>); and chloroplast\u00a0<span class=\"caps\">RNA<\/span>\u00a0binding proteins. These findings suggest that\u00a0<span class=\"caps\">ATGRP<\/span>\u00a0proteins have an evolutionarily conserved function in the regulation of gene expression at the posttranscriptional level in response to environmental stress.<\/p>\n","protected":false},"template":"","display_control":[],"_links":{"self":[{"href":"https:\/\/ladomerylab.org\/wp-json\/wp\/v2\/research_papers\/590"}],"collection":[{"href":"https:\/\/ladomerylab.org\/wp-json\/wp\/v2\/research_papers"}],"about":[{"href":"https:\/\/ladomerylab.org\/wp-json\/wp\/v2\/types\/research_papers"}],"wp:attachment":[{"href":"https:\/\/ladomerylab.org\/wp-json\/wp\/v2\/media?parent=590"}],"wp:term":[{"taxonomy":"display_control","embeddable":true,"href":"https:\/\/ladomerylab.org\/wp-json\/wp\/v2\/display_control?post=590"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}